Welcome to the Kunjapur Lab Homepage

​Our lab uses genetic engineering to expand the kinds of chemistry that microbes can perform.
​By creating new possibilities in microbial chemistry, we strive to solve applied problems in industries ranging from energy to healthcare.

We are part of the Chemical & Biomolecular Engineering Department at the University of Delaware
and affiliated with the Delaware Biotechnology Institute and the Delaware Environmental Institute.

Tools

Metabolic Engineering

The field of metabolic engineering has made tremendous strides over the last two decades, enabling commercialization of a diverse array of products. Yet, many functional groups remain difficult to introduce into small molecules.

Genome Engineering

Genome engineering, editing, and assembly technologies have advanced rapidly during the last decade. Natural microbial genomes contain many components that hinder our ability to expand biochemistry but can be edited using approaches such as MAGE and CRISPR-Cas9.

Protein Engineering

Proteins serve valuable roles as biocatalysts, biomaterials, and therapeutics. The ability to augment protein structures and functions through the incorporation of amino acids beyond the natural 20 can improve protein performance in each of these roles. 

Synthetic Biology

We are part of the synthetic biology community that strives to make biology easier to engineer. Examples of such efforts include the characterization of biological parts, the refinement of gene expression strategies, and the improvement of enabling technologies such as gene synthesis and sequencing. (Image from MIT RLE)

Vision

Recent Lab News

Imagine a future where everything needed for society can be grown from just sunlight and CO2, and where engineered cells inside your body have an augmented ability to sense and respond to disease. ​By expanding the chemistry capable in living systems, we can produce chemicals sustainably and achieve breakthroughs in diagnostics and treatments. Join our team and help us bring this future closer to  reality.

Jan 2020:
Aditya joined the Engineering Biology Research Consortium

Dec 2019:
Soumili Chattopadhyay joined the lab - welcome Soumili!

Dec 2019:
Morgan's review on biosynthesis of nonstandard chemical functional groups is accepted - congrats Morgan!

Oct 2019:
Neil's review on CARs is accepted - congrats Neil!

May 2019:
Michaela Jones joined the lab after her CBI rotation - welcome Michaela!

Feb 2019:
Aditya was awarded an ELBI (Biosecurity) Fellowship

Jan 2019:
Lab opening

Nov 2018:
Welcome new PhD students -
Neil Butler
Sabyasachi Sen
Morgan Sulzbach